He's done so previously in popular movies like Se7en, 21, Horrible Bosses and Superman Returns.
Not to mention, he's also currently portraying a ruthless politician on Netflix's critically-acclaimed show House of Cards.
But the widely-talented Spacey is lending his likeness and voice to a new role, albeit with a similar tone.
The 54-year-old has been tapped to be the villain in the upcoming incarnation of "Call of Duty," which is set to come out for Xbox 360 and PlayStation 4 on Nov. 4.
Even in animated form, Spacey still can command the screen.